THE SPIROCHÆTA PALLIDA (TREPONEMA PALLIDUM) IN SYPHILIS.

Spirochæta (treponema) Pallida and Syphilis

The extensive bibliography on experimental syphilis and spiroch~eta pallida has been brought together and reviewed recently by Hoffmann, 1 Neisser, 2 R. Kraus, 3 Glass, 4 and Buschke and Fischer, 5 in whose publications the present state of our knowledge on these subjects can be readily found. The weight of opinion is strongly in favor of accepting the transmissibility of the syphilitic virus t...

Spirochæta Pallida (Spironema Pallidum) in Syphilis

Agglutination of Treponema Pallidum in Human Syphilis

The results observed with this strain of Treponema pallidum may be stated as follows: 1. Normal human serum did not agglutinate this culture of Treponema pallidum in dilutions of 1:5 or higher; equal parts of treponema culture and normal serum (dilution 1:2) resulted in agglutination in about 50 per cent of the sera. With the strain of Treponema pallidum used in this study specific agglutinatio...

Studies on Treponema Pallidum and Syphilis

Although antibodies can be produced by the immunization of animals with cultivated Treponema pallidum, and although these antibodies exert specific agglutinative and treponemicidal action upon the culture organisms, they possess, at least in the concentration so far obtained by us in rabbits and sheep, practically no action for virulent treponemata obtained directly from lesions. There seems to...

Studies on Treponema Pallidum and Syphilis. Ii. Spiroch~ticidal Antibodies against Treponema Pallidum. by Hans

In a previous communication we have reported on the agglufinins which are formed in rabbits following systematic inoculation with concentrated culture material of Treponema pallidum. Incidentally it may be stated that a sheep has also been successfully used. The antigen used for the immunization of these animals was similar to that employed in the first agglutination experiments, except that we...